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Independent analysis of data by Columbia University on suicidal ideation SI ; and adolescents Elevation of suicidal ideation Efexor clearly has a higher rate of SI with adolescent depressed population vs. no drug control groups 8.8 times increase of SI Next highest is Paxil at 2.65 There was NO increased rate of actual completed suicides with this group on Ffexor only SI Note: Wyeth wanted this on label and FDA said `no' and emsam. Effexor xr should be used during pregnancy only if clearly needed. RTOG Institution # RTOG 0522 Case # N ; N ; ELIGIBILITY CHECKLIST 1 8 07 ; page 2 of 3 ; 16. Has the patient had initial surgical treatment other than the diagnostic biopsy of the primary site or nodal sampling of neck disease? 17. Does the patient have any of the severe comorbid conditions listed in Section 3.2.6 that would exclude him her from participation, including the following CTCAE, v. 3.0 electrolyte abnomalities? Calcium 7 mg dl or 12.5 mg dl; Glucose 40 mg dl or 250 mg dl; Magnesium 0.9 mg dl or 3 mg dl Potassium 3 mmol L or 6 mmol L; Sodium 130 mmol L or 155 mmol L 18. Has the patient had a prior allergic reaction to the study drugs involved in this protocol? 19. Has the patient had prior therapy that specifically and directly targets the EGFR pathway? 20. Has the patient signed a study-specific consent form? and geodon. Singulair Step Therapy 1. Certification for Singulair is approved for members with Asthma. 2. For children 5 years of age, exceptions can be made for Singulair certification. 3. For members with allergic rhinitis, Singulair is not covered. 4. Members with chronic urticaria should have tried one of the oral antihistamines Zyrtec D ; or hydroxyzine. 5. Members with atopic dermatitis should have tried a prescription topical corticosteroid or a topical immunomodulator Elidel, Protopic ; . If one of these drugs has been tried, then approve Singulair. 6. Infants with acute respiratory syncytial virus RSV ; bronchiolitis. Approve Singulair. Celebrex Step Therapy 1. If a member has tried one 1 ; prescription strength NSAIDS nonsteroidal anti-inflammatory ; may be generic or brand ; for the current condition, then certification for a formulary single source COX-2 Inhibitor [ Celebrex 30 pill limit per month supply ; ] may be given at the 3rd tier copay. 2. Generic Naproxen 500mg. will be offered to all members at ##TEXT## copay. 3. Generic Ibuprofen 600mg and 800mg will be offered to all members for a generic copay. 4. Mobic will be offered at the 3rd tier copay but does not apply to the step therapy guidelines. 5. Exceptions for formulary coverage at a 2nd tier copay can be made for members that meet one of the following criteria: Age 65 Past history of a GI bleed, perforation, obstruction. Requires use of long-term 1 month ; oral corticosteroids therapy. Currently taking warfarin Coumadin - DuPont Pharma ; or dicumarol. Diagnosis of rheumatoid arthritis. 6. Certification for formulary Celebrex 30 pill limit per month supply ; may be given for patients with reduced platelets counts 75, 000. Antidepressent SSRI and SNRI ; Step Therapy 1. One generic drug will be required before a brand name drug is authorized. Generic drugs will have to have been prescribed at an effective dose for a minimum of 30 days. Documentation of attempt and failure of a generic within the last 12 months will be considered as fulfilling this requirement. The daily effective doses are considered to be: o Fluxoetine 40 mg. o Paroxetine 20 mg. o Citalopram 40 mg. o Mirtazapine 30mg. o Bupropion sr 300mg. o Sertraline 150 mg. when becomes generic ; 2. Second tier drugs are Lexapro, Zoloft until it becomes generic ; , Wellbutrin XL, Effexor, and Paxil CR. 3. Cymbalta will be third tier for all diagnoses. 4. Effexkr will not be covered for the diagnosis of perimenopausal symptoms until one generic SSRI has been tried. Antiemetic Step Therapy Zofran, Aloxi, Anzemet ; This step therapy only applies to Members receiving Chemotherapy. 1. Zofran is the preferred drug for Level 1 and Level 2 Chemotherapy Agents. 2. Anzemet will be covered for these agents if Zofran fails. 3. Aloxi will not be covered for Level 1 and Level 2 agents without prior authorization. 4. Aloxi will be covered for agents in Level 3, 4, and 5. Prior authorization is not required. 5. Zofran is the only covered outpatient oral agent that a Member can obtain from a retail pharmacy.

Augmented response in terms of overall well being and quality of life was observed in older depressed women treated with sertraline Zoloft ; and estrogen therapy, 52 compared to those receiving sertraline alone. A pooled analysis of women with depression treated with venlafaxine Effexor ; compared to SSRIs found no evi dence of an age by treatment interaction, suggesting that the antidepressant response obtained with ven lafaxine would not be affected in the presence of a 53 hypo estrogenic state. 54 With respect to prospective studies, Prange et al. did not find any difference in efficacy among younger 2045 years of age ; women with MDD randomized in a double blind fashion to receive co initiation treat ment with imipramine and estrogen versus imipramine alone. Similarly, a number of case reports and small, open label trials suggest the potential utility of estro 40, 55, 56 To date, there has gen augmentation in TRD.

How long to get effexor out of system A 1991 NIH Consensus Panel on the Treatment of Panic Disorder consensus.nih.gov 1991 1991PanicDisorder085html ; determined that "Several different classes of treatment have been shown to be clinically effective, including cognitive and behavioral, pharmacologic, and combinations of the two. The most commonly used behavioral approach is graduated exposure, aimed primarily at reducing phobic avoidance and anticipatory anxiety. Cognitive-behavioral approaches, developed more recently, also treat panic attacks directly. These treatments involve cognitive restructuring, that is, changing of maladaptive thought processes and are generally used in combination with a variety of behavioral techniques, including breathing retraining and activities that target exposure to bodily sensations and external phobic situations." SSRIs Serotonin-Specific Reuptake Inhibitors ; are the most useful of the current medications for the pharmacologic treatment of panic disorder. Both paroxetine Paxil and generic ; and fluoxetine Prozac and generic ; are FDA approved for Panic Disorder, but all SSRIs are effective, perhaps equally so. The sedating effect of paroxetine may be calming, whence helpful. Activating SSRIs such as fluoxetine may need to be started at lower doses. Other antidepressants, such as tricyclics, MAOIs, and venlafaxine Effexor ; are also likely effective but may have more adverse reactions. Buspirone BuSpar ; is not useful as monotherapy for panic disorder. Beta-blockers are also not effective. One reasonable approach for patients with panic disorder and comorbid depression is to begin with 5 or 10 mg a day of paroxetine for 1 to 2 weeks, then increase the dosage by 10 mg a day every 1 to 2 weeks. If sedation becomes intolerable, then taper paroxetine down to 10 mg a day and switch to fluoxetine at 10 mg a day and titrate upward slowly. Kaplan & Sadock, Synopsis of Psychiatry, 8th Edition Although SSRIs are the most useful long-term pharmacologic treatment for panic disorder, they require some weeks to take effect, which may present a challenge to many patients. If immediate relief seems necessary but a patient's sense of urgency and seroquel. How long to get effexor out of system William Alto: Patients threaten with calls to the office if they are placed on generic. Jessica Oesterheld: Wants to study this more. Motion to accept the way they are submitted- a group of preferred antidepressants including but not overly favoring any member. Need education, change Fluoxetine to a 1 later in time with grandfather existing. 8 approved 1 abstained 1 absent Jabbar Fazeli objects to motion to exempt Zoloft for age 65 and over while study is occurring. 1 approved 8 opposed 1 abstained Motion: table discussion until there is further research 9 approved 1 opposed Miscellaneous Anti-Depressants Effexor tabs an 8? If it's a 4, it may be used as an SSRI--fluoxetine alternative. Tim Clifford: Join this class to the SSRI class. Jabbar Fazeli: Wants an exclusion for 65. Jessica Oesterheld: Wants to emphasize safety in elderly re older agents. Move this class in with SSRI's 10 approved votes Make maprotiline an 8 10 approved votes Re-vote Effexor tabs as 4 or until further research is done Leave Effexor at 4 3 approved Study Effexor further before assigning any ranking 0 approved Make Effexor remaining an 8 approved, 1 opposed, 1 abstained Motion to make amoxapine an 8 and grandfather like other antidepressants 10 approved. Motion to make amitriptyline an 8 for the elderly 65 for new scripts 7 approved, 2 opposed, 1 abstained purely clinical-sr's not eligible for consideration ; Motion to make all in this class an 8 except Nortriptyline for over 65 10 approved. How long to get effexor out of system Osteoporosis prevention archives dr stoll or anyone, is osteoperosis curable in a young person and sarafem. Does effexor cause weight gain Medication There are more than 20 antidepressant drugs currently available. Antidepressants correct the chemical imbalance in the brain. Because a variety of drugs target different neurotransmitters and imbalances of these neurotransmitters can vary from patient to patient, some drugs may be more effective than others for any individual. Sometimes a combination of drugs is best. There are four 4 ; groups of antidepressant medications most commonly used to treat depression: * Tricyclic antidepressants TCAs ; , which include: amitriptyline Elavil ; imipramine Trofanil, Janimine ; nortryptyline Pamelor ; despiramine Norpramin ; TCAs work by slowing the rate at which neurotransmitters chemical messengers ; reenter brain cells. This increases the concentration of the neurotransmitters in the central nervous system which relieves depression. * Monoamine oxidase inhibitors MAOIs ; include phenelzine Nardil ; and tranylcypromine Parnate ; . MAO is an enzyme responsible for breaking down certain neurotransmitters in the brain. MAOIs inhibit this enzyme and restore more normal mood states. * Lithium carbonates, including Eskalith and Lithobid. Lithium reduces excessive nerve activity in the brain by altering the chemical balance within certain nerve cells. This drug is effective is treating bipolar disorder. * Selective serotonin reuptake inhibitors SSRIs ; include: fluoxetine Prozac ; fluvoxamine Luvox ; paroxetine Paxil ; sertraline Zoloft ; citalopram Celexa ; escitalopram oxalate Lexapro ; SSRIs act specifically on serotonin, making it more available for nerve cells, thus easing the transmission of messages without disrupting the chemistry of the brain. Two other antidepressants that affect two neurotransmitters, serotonin and norepinephrine, are venlafaxine Effexor ; and nefazodone Serzone ; . Another of the newer antidepressants, bupropion Wellbutrin ; , is chemically unrelated to the other antidepressants. It has more effect on norepinephrine and dopamine than on serotonin. Medication usually produces a marked improvement by six weeks, but may require up to 12 weeks for full effect. Psychotherapy Psychotherapy involves talking to family doctor, counselor or therapist about things that are occurring in a person's life. The aim of psychotherapy is to remove all symptoms of depression and return a person to a normal life. There are three psychotherapies available to treat depression: behavioral therapy, cognitive therapy or interpersonal therapy. Behavioral therapy focuses on current behaviors, cognitive therapy focuses on thoughts and thinking patterns, and interpersonal therapy focuses on current relationships. An SSRI comparator [poster]. Presented at the 156th annual meeting of the American Psychiatric Association; May 1722, 2003; San Francisco, Calif Ansari A. The efficacy of newer antidepressants in the treatment of chronic pain: a review of current literature. Harv Rev Psychiatry 2000; 7: 257277 Reisner L. Antidepressants for chronic neuropathic pain. Curr Pain Headache Rep 2003; 7: 2433 Casper RC, Katz MM, Bowden CL, et al. The pattern of physical symptom changes in major depressive disorder following treatment with amitriptyline or imipramine. J Affect Disord 1994; 31: 151164 Watson CP, Vernich L, Chipman M, et al. Nortriptyline versus amitriptyline in postherpetic neuralgia: a randomized trial. Neurology 1998; 51: 11661171 Graff-Radford SB, Shaw LR, Naliboff BN. Amitriptyline and fluphenazine in the treatment of postherpetic neuralgia. Clin J Pain 2000; 16: 188192 Raja SN, Haythornthwaite JA, Pappagallo M, et al. Opioids versus antidepressants in postherpetic neuralgia: a randomized, placebo-controlled trial. Neurology 2002; 59: 10151021 Descombes S, Brefel-Courbon C, Thalamas C, et al. Amitriptyline treatment in chronic drug-induced headache: a double-blind comparative pilot study. Headache 2001; 41: 178182 Bendtsen L, Jensen R. Amitriptyline reduces myofascial tenderness in patients with chronic tension-type headache. Cephalalgia 2000; 20: 603610 Holroyd KA, O'Donnell FJ, Stensland M, et al. Management of chronic tension-type headache with tricyclic antidepressant medication, stress management therapy, and their combination: a randomized controlled trial. JAMA 2001; 285: 22082215 Arnold LM, Keck PE Jr, Welge JA. Antidepressant treatment of fibromyalgia: a meta-analysis and review. Psychosomatics 2000; 41: 104113 Lang E, Hord AH, Denson D. Venlafaxine hydrochloride Effexor ; relieves thermal hyperalgesia in rats with an experimental mononeuropathy. Pain 1996; 68: 151155 Enggaard TP, Klitgaard NA, Gram LF, et al. Specific effect of venlafaxine on single and repetitive experimental painful stimuli in humans. Clin Pharmacol Ther 2001; 69: 245251 Kathpal GS. Role of SSRIs in the management of migraine. Headache Quarterly Curr Treat Res 1998; 9: 265266 Kunz NR. Effect of Venlafaxine Extended Release on Diabetic Neuropathic Pain [poster]. Presented at the 153rd annual meeting of the American Psychiatric Association; May 1318, 2000; Chicago, Ill Sindrup SH, Bach FW, Madsen C, et al. Venlafaxine versus imipramine in painful polyneuropathy: a randomized, controlled trial. Neurology 2003; 60: 12841289 Tasmuth T, Hartel B, Kalso E. Venlafaxine in neuropathic pain following treatment of breast cancer. Eur J Pain 2002; 6: 1724 Adelman LC, Adelman JU, Von Seggern R, et al. Venlafaxine extended release XR ; for the prophylaxis of migraine and tension-type headache: a retrospective study in a clinical setting. Headache 2000; 40: 572580 Dryson E. Venlafaxine and fibromyalgia [letter]. N Z Med J 2000; 113: 87 Dwight MM, Arnold LM, O'Brien H, et al. An open clinical trial of venlafaxine treatment of fibromyalgia. Psychosomatics 1998; 39: 1417 Sumpton JE, Moulin DE. Treatment of neuropathic pain with venlafaxine. Ann Pharmacother 2001; 35: 557559 Taylor K, Rowbotham MC. Venlafaxine hydrochloride and chronic pain. West J Med 1996; 165: 147148 Songer DA, Schulte H. Venlafaxine for the treatment of chronic pain [letter]. J Psychiatry 1996; 153: 737 Pernia A, Mico JA, Calderon E, et al. Venlafaxine for the treatment of neuropathic pain. J Pain Symptom Manage 2000; 19: 408410 Durand JP, Goldwasser F. Dramatic recovery of paclitaxel-disabling neurosensory toxicity following treatment with venlafaxine. Anticancer Drugs 2002; 13: 777780 Schreiber S, Vinokur S, Shavelzon V, et al. A randomized trial of fluoxetine versus amitriptyline in musculo-skeletal pain. Isr J Psychiatry Relat Sci 2001; 38: 8894 Arnold LM, Hess EV, Hudson JI, et al. A randomized, placebo-controlled, double-blind, flexible-dose study of fluoxetine in the treatment of women with fibromyalgia. J Med 2002; 112: 191197 Sindrup SH, Bjerre U, Dejgaard A, et al. The selective serotonin reuptake inhibitor citalopram relieves the symptoms of diabetic neuropathy. Clin Pharmacol Ther 1992; 52: 547552 and sinequan! Steadyhealth - health topics forum index - ear, nose, throat, and dental problems - throat disorders all times are gmt - 5 hours my navigator unanswered posts end poll - information on this site is provided for informational purposes only. I take 200mg daily of wellbutrin , 150mg daily of effexor and 75mg nightly of zopiclone and buspar. As with any psychotropic drug, effexor may impair judgment, thinking, or motor skills, and patients should be advised to exercise caution until they have adapted to therapy. All answers show answers by: date rating paulette g sat oct 28 : 00 edt 2006 i took effexor xr for 4 years and tried to get off of it and atarax and Buy cheap effexor online. The first integrase inhibitor, raltegravir, is available now through a special program called an "Expanded Access Program" ; from Merck. The first CCR5 inhibitor or CCR5 antagonist ; , maraviroc, is also available through an expanded access program from Pfizer see "How to Get New Anti-HIV Drugs" below ; . After FDA approval availability transfers to the pharmacy. Doctors group anti-HIV drugs by how they work against HIV. Drugs may affect a part of HIV itself. Or they may affect a part of the CD4 cell that HIV infects. Table 3 and Figure 2 list the nine main groups of anti-HIV drugs and explain where and how they work. Richardson Dep. at 81; J. Richardson Dep. at 145. ; On August 23, 2003, Plaintiff ingested 200 Benadryl tablets in a further attempt to commit suicide. D. Richardson Dep. at 83. ; As a result of his actions, Richardson was again hospitalized. Knott discontinued his treatment on Lexapro and, in its place, prescribed the anti-depressant Effexor. Knott Dep. at 40-41. ; Unlike Paxil and Lexapro, Effexor is not an SSRI, but does have an SSRI component. Id. ; However, less than three weeks later, on September 23, 2003, Richardson once again attempted to overdose, this time by ingesting 200 Benadryl tablets and consuming six 24ounce beers. J. Richardson Dep. at 143. ; While in intensive care for the effects of the Benadryl, it was discovered that Richardson had bilateral pneumonia, the likely result of his last overdose on the drug. J. Richardson Dep. at 144. ; Knott continued to treat Richardson during his hospitalization and following his discharge around October 3, 2003. J. Richardson Dep. at 142. ; In November, 2003 Richardson complained to Knott about suicidal thoughts, however, he did not further act on these ideas. Knott Dep. at 48. ; Knott discontinued Richardson's treatment with anti-depressants in March 2004. However, after his condition worsened, Plaintiff again began anti-depressant treatment. Knott Dep. at 46. ; Since taking Paxil, Richardson's depression has also been treated with Lexapro, Effexor and Cymbalta. Id. at 40-41, 46-47. ; As of July 15, 2005, Knott has been treating Richardson for Major Depressive Disorder. Id. at 46. ; As part of that treatment, Plaintiff takes Antabuse for alcohol dependance, Cymbalta for depression, and Trazodone and Gabitril for sleeping. Id. at 48. ; Plaintiff commenced this action on August 10, 2004 seeking million in compensatory and punitive damages for the personal injuries he suffered as a result of the suicides attempts allegedly caused by Paxil. On November 18, 2005, GSK filed the instant motion for summary judgment to and pamelor. In point-chin and guilt, sure days, society orders, look vicinity, arrayed and carded communications, interested reasons, the english needed like feathers in a heart lock. Some of the difficulty in identifying causes of PD stems from how one defines the disease; i.e., by brain pathology or by responsiveness to dopaminergic medication. Accuracy of the clinical diagnosis of PD was reviewed: about 10% of rigorously classified PD are not found to be PD when examined pathologically. When pathological diagnosis is used, about 6% of autopsy proven cases of PD have atypical symptoms. Up to 5% of patients in a movement disorders subspecialty clinic are incorrectly classified. There may be clinical subtypes of PD that include a tremor-dominant, postural instability gait. How to withdraw from effexor xr Mootha’ s group decided to query their toolkit and see if there were any drugs that affected both of these functions— drugs that could boost gene expression while reducing mitochondrial waste. When looking at the median time to symptomatic recurrence for symptomatic patients, it appeared to be useful when going out to 125 days or so. Effexor norepinephrine effect He eventually asked to become a salesman and within a few years his efforts resulted in the addition of many new and large accounts and buy emsam. C27 777.1 Barx1 is necessary for zebrafish cranial neural crest patterning and pharyngeal arch chondrogenesis. S. Sperber and I. Dawid. NICHD, NIH. C28 777.2 Development of an experimental model for the study of the ossification of the petro-occipital fissure and its ties to age-related hearing loss. H.M. Salinas, A.Y. Yemin, A.L. Balboni, J.S. Reidenberg, A.D. Bergemann, P.J. Gannon, E.E. Smouha and J.T. Laitman. Mount Sinai Sch. of Med. C29 777.3 A case of extensive hyperostosis frontalis interna in an 87-year-old, female human cadaver. A.D. Prather, E.F. Talarico, Jr. and K.D. Hardt. Indiana Univ. Sch. of Med.Northwest. C30 777.4 Evidence that the mutation responsible for osteopetrosis in the op rat is not contained within the coding region of the Slc9a3r2 gene. D.E. Dobbins and M.M. Dobbins. Uniformed Svcs. Univ. of Hlth. Sci. C31 777.5 An experimental study of the effects of nicotine on the intervertebral disc. N.M. Afifi and K.A. Hafez. Qatar Univ. and Ain Shams Univ., Egypt. C32 777.6 Expression of NPR-B and CNP mRNA during the course of chick embryonic limb development: implication in the regulation of limb mesenchymal chondrogenesis. A.C. Tufan. Pamukkale Univ. Sch. of Med., Turkey. C33 777.7 Gelatinase activity in joints of a mucopolysaccharidosis model. E.L. Bray, P.M. Mattioli, C.M. Simonaro, M.E. Haskins and M. D'Angelo. Philadelphia Col. of Osteo. Med., Mount Sinai Sch. of Med. and Univ. of Pennsylvania Sch. of Vet. Med. C34 777.8 Zygapophysial joint adhesions following induced segmental hypomobility in the rat. G.D. Cramer, J.W. Little, C.N.R. Henderson and C. Daley. Natl. Univ. of Hlth. Sci., Lombard, IL and Palmer Ctr. for Chiropractic Res., Davenport, IA. C35 777.9 Hypertrophic chondrocyte production and secretion of a unique TGFb2 large latent complex. B.N. Dragann, S.E. Day, B.M. Mentzer, D. Appelt, V.L. Scheinfeld, P.M. Mattioli and M. D'Angelo. Philadelphia Col. of Osteo. Med. C36 777.10 Molecular players involved in TGF-1 induced CTGF CCN2 expression in primary rat osteoblasts: SBE, TRE and SRC ERK. J.A. Arnott, A. Sanjay, T.A. Owen, J. Litvin, F.F. Safadi and S.N. Popoff. Temple Univ. Sch. of Med. and Pfizer Global R&D. Nurture the person with offers of favorite foods or soothing or inspirational activities. Reassure the person that he or she will not be abandoned. Consider supportive psychotherapy and or a support group, especially an early-stage group for people with Alzheimer's who are aware of their diagnosis and prefer to take an active role in seeking help or helping others. Pharmaceutical approaches Physicians often prescribe antidepressants for treatment of depressive symptoms in Alzheimer's. The most commonly used medications are in a class of drugs called selective serotonin reuptake inhibitors SSRIs ; . These include citalopram Celexa ; , sertraline Zoloft ; , paroxetine Paxil ; and fluoxetine Prozac ; . Physicians may also prescribe antidepressants that inhibit the reuptake of brain chemicals other than serotonin, including venlafaxine sold as Effexor and Effexor-SR ; , mirtazapine Remeron ; and bupropion Wellbutrin ; . Antidepressants in a class called the tricyclics, which includes nortriptyline Pamelor ; and desipramine Norpramine ; , are no longer used as firstchoice treatments, but are sometimes used when individuals do not benefit from other medications. Where can I get more information? The proposed diagnostic criteria for "depression of Alzheimer's disease" are described in: Olin, J.T.; Schneider, L.S.; Katz, I.R.; et al. "Provisional Diagnostic Criteria for Depression of Alzheimer's Disease." American Journal of Geriatric Psychiatry 2002; 10: 125 On pages 129 141 following the article, there is a commentary by the authors discussing rationale and background for the criteria. The Alzheimer's Association, the world leader in Alzheimer research, care and support, is dedicated to finding prevention methods, treatments and an eventual cure for Alzheimer's. 24 7 Helpline 1.800.272.3900 TDD Access 312.335.8882 Web site alz e-mail info alz Fact sheet updated February 10, 2003! I have been on effexor for the past year and my memory has gotten worst. 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Duloxetine hydrochloride is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and a weak inhibitor of dopamine reuptake. Its properties are most similar to those of venlafaxine Effexor, Effexor XR ; , and the two agents are designated as serotonin and norepinephrine reuptake inhibitors SNRIs ; .Their inhibition of norepinephrine reuptake distinguishes them from the selective. Please do not include antisocial personality or borderline personality disorder. * Common psychiatric medications: Ativan lorazepam ; Geodon ziprasidone ; Buspar buspirone ; Haldol haloperidol ; Celexa citalopram ; Klonopin clonazepam ; Clorazil clozapine ; Lamictal lamotrigene ; Depakote valproic acid ; Lithobid lithium ; Desyrel trazodone ; Nardil phenelzine ; Effexor venlafaxine ; Neurontin gabapentin ; Elavil amitriptyline ; Pamate tranylcypromine. DISPENSING A. Drug-related problem detected during new order screening B. Dosage Range 1. Amitriptyline Elavil, Endep ; Adult: PO 25-300 mg day 2. Amoxapine Ascendin ; Adult: PO 25-600 mg day 3. Bupropion Wellbutrin ; C & A: PO 50-450 mg day or 3-6 mg kg day Adult: PO 50-450 mg day Bupropion Wellbutrin XR ; Adults : 75-400mg day 4. Clomipramine Anafranil ; C & A: PO 50-250 mg day or 2-3 mg kg day Adult: PO 50-250 mg day 5. Desipramine Norpramin ; C & A: PO 50-250 mg day or 2-5 mg kg day Adult: PO 50-300 mg day 6. Doxepin Sinequan, Adapin ; Adult: PO 25-300 mg day 7. Fluoxetine Prozac ; C & A: PO 10-60 mg day Adult: PO 20-80 mg day 8. Imipramine Tofranil ; C & A: PO 25-250 mg day or 2-5 mg kg day Adult: PO 20-300 mg day 9. Nefazodone Serzone ; Adult: PO 100-600 mg day 10. Nortriptyline Pamelor, Aventyl ; C & A: PO 50-125 mg day or 1-3 mg kg day Adult: PO 50-200 mg day 11. Paroxetine Paxil ; C & A: PO 10-60 mg day or 0.25-0.7 mg kg day Adult: PO 10-60 mg day 12. Sertraline Zoloft ; C & A: PO 50-200 mg day or 1-3 mg kg day Adult: PO 50-200 mg day 13. Trazodone Desyrel ; C & A: PO 100-800 mg day or 2-5 mg kg day Adult: PO 100-800 mg day 14. Venlafaxine Effexor ; C & A: PO 75-375 mg day or 1-3 mg kg day Adult: PO 75-375 mg day Venlafaxine Effexor XR ; Adults: 37.5-225mg DAY C. Duration of Therapy 1. Treatment should be for at least 14 days with the same drug D. Dosage 1. Should be regularly scheduled 2. Prn use not acceptable 3. Doses may be single or divided E. Route 1. Concentrate switched to tabs caps before discharge 100% Must justify any variance in dose in the progress notes. NOTE: No single dose of wellbutrin should be greater than 150 mg dose. Dose interval should be 4 hours. No single dose of Wellbutrin XR should be greater than 200mg dose. Clomipramine is indicated for For OCD only. 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